Semi-rational design of psychrophilic cellobiose 2-epimerase for improved substrate affinity and enhanced low-temperature epimerization activity.

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Bibliographic Details
Title: Semi-rational design of psychrophilic cellobiose 2-epimerase for improved substrate affinity and enhanced low-temperature epimerization activity.
Authors: Xu H; College of Ecology, Lanzhou University, Lanzhou 730000, China; Center for Pan-third Pole Environment, Lanzhou University, Lanzhou 730000, China; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China; Chayu Integrated Observation and Research Station of the Xizang Autonomous Region, Xizang, China. Electronic address: xuh2023@nanoctr.cn., Lv N; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China; National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: lvnn2022@nanoctr.cn., Liu Y; Center for Pan-third Pole Environment, Lanzhou University, Lanzhou 730000, China; Chayu Integrated Observation and Research Station of the Xizang Autonomous Region, Xizang, China; State Key Laboratory of Tibetan Plateau Earth System, Environment and Resources (TPESER), Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China. Electronic address: yqliu@itpcas.ac.cn.
Source: Bioresource technology [Bioresour Technol] 2026 Jun; Vol. 449, pp. 134363. Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2976
DOI:10.1016/j.biortech.2026.134363