Semi-rational design of psychrophilic cellobiose 2-epimerase for improved substrate affinity and enhanced low-temperature epimerization activity.

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Title: Semi-rational design of psychrophilic cellobiose 2-epimerase for improved substrate affinity and enhanced low-temperature epimerization activity.
Authors: Xu H; College of Ecology, Lanzhou University, Lanzhou 730000, China; Center for Pan-third Pole Environment, Lanzhou University, Lanzhou 730000, China; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China; Chayu Integrated Observation and Research Station of the Xizang Autonomous Region, Xizang, China. Electronic address: xuh2023@nanoctr.cn., Lv N; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China; National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: lvnn2022@nanoctr.cn., Liu Y; Center for Pan-third Pole Environment, Lanzhou University, Lanzhou 730000, China; Chayu Integrated Observation and Research Station of the Xizang Autonomous Region, Xizang, China; State Key Laboratory of Tibetan Plateau Earth System, Environment and Resources (TPESER), Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China. Electronic address: yqliu@itpcas.ac.cn.
Source: Bioresource technology [Bioresour Technol] 2026 Jun; Vol. 449, pp. 134363. Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Semi-rational design of psychrophilic cellobiose 2-epimerase for improved substrate affinity and enhanced low-temperature epimerization activity.
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  Data: <searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; College of Ecology, Lanzhou University, Lanzhou 730000, China; Center for Pan-third Pole Environment, Lanzhou University, Lanzhou 730000, China; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China; Chayu Integrated Observation and Research Station of the Xizang Autonomous Region, Xizang, China. Electronic address: xuh2023@nanoctr.cn.<br /><searchLink fieldCode="AU" term="%22Lv+N%22">Lv N</searchLink>; CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China; National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: lvnn2022@nanoctr.cn.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Center for Pan-third Pole Environment, Lanzhou University, Lanzhou 730000, China; Chayu Integrated Observation and Research Station of the Xizang Autonomous Region, Xizang, China; State Key Laboratory of Tibetan Plateau Earth System, Environment and Resources (TPESER), Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100101, China. Electronic address: yqliu@itpcas.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%229889523%22">Bioresource technology</searchLink> [Bioresour Technol] 2026 Jun; Vol. 449, pp. 134363. <i>Date of Electronic Publication: </i>2026 Mar 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Applied+Science%22">Elsevier Applied Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9889523 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2976 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209608524%22">09608524 </searchLink><i>NLM ISO Abbreviation: </i>Bioresour Technol <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.biortech.2026.134363
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        StartPage: 134363
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      – TitleFull: Semi-rational design of psychrophilic cellobiose 2-epimerase for improved substrate affinity and enhanced low-temperature epimerization activity.
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            NameFull: Xu H
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            NameFull: Lv N
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            NameFull: Liu Y
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            – D: 01
              M: 06
              Text: 2026 Jun
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              Y: 2026
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              Value: 449
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            – TitleFull: Bioresource technology
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