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Specific Deficiency of Naïve CD4+ T Lymphocytes Characterizes Heart Failure and Heightens Mortality Risk in the HRS.

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Title: Specific Deficiency of Naïve CD4+ T Lymphocytes Characterizes Heart Failure and Heightens Mortality Risk in the HRS.
Authors: Zidar DA; Heart Vascular and Thoracic Institute and the Department of Cardiovascular and Metabolic Sciences Cleveland Clinic Foundation Cleveland OH USA.; Case Western Reserve University School of Medicine Cleveland OH USA.; Louis Stokes Cleveland Veterans Affairs Medical Center Cleveland OH USA., Freeman ML; Case Western Reserve University School of Medicine Cleveland OH USA.; Division of Infectious Disease and HIV Medicine, Department of Medicine Case Western Reserve University School of Medicine Cleveland OH USA., Wilson BM; Louis Stokes Cleveland Veterans Affairs Medical Center Cleveland OH USA., Al-Kindi S; Houston Methodist DeBakey Heart and Vascular Center Houston TX USA., Chung MK; Heart Vascular and Thoracic Institute and the Department of Cardiovascular and Metabolic Sciences Cleveland Clinic Foundation Cleveland OH USA.; Case Western Reserve University School of Medicine Cleveland OH USA., Gunzler DD; Center for Healthcare Research and Policy Case Western Reserve University at MetroHealth Cleveland OH USA., Parikh SA; Division of Cardiology, Center for Interventional Vascular Therapy Columbia University Irving Medical Center New York NY USA., Sharma AA; Department of Pathology and Laboratory Medicine Emory University School of Medicine Atlanta GA USA., Shive CL; Louis Stokes Cleveland Veterans Affairs Medical Center Cleveland OH USA., Jain M; Department of Molecular Biology, Cell Biology and Biochemistry The Warren Alpert Medical School of Brown University Providence RI USA., Skarbinski J; Division of Research Kaiser Permanente Northern California Oakland CA USA., Tang WHW; Heart Vascular and Thoracic Institute and the Department of Cardiovascular and Metabolic Sciences Cleveland Clinic Foundation Cleveland OH USA., Dalton JE; Division of Infectious Disease and HIV Medicine, Department of Medicine Case Western Reserve University School of Medicine Cleveland OH USA., Anthony DD; Case Western Reserve University School of Medicine Cleveland OH USA.; Louis Stokes Cleveland Veterans Affairs Medical Center Cleveland OH USA., Chan TA; Center for Immunotherapy and Immuno-Oncology Cleveland Clinic Foundation Cleveland OH USA., Thyagarajan B; Department of Laboratory Medicine and Pathology University of Minnesota Minneapolis MN USA.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 Mar 17; Vol. 15 (6), pp. e042475. Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
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              Text: 2026 Mar 17
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