Effect of Preoperative Esketamine Nebulized Inhalation on Cough Reflex, Sedation, and Postoperative Sore Throat in Extubation of Surgical Patients: A Prospective, Double-Blind, Randomized Controlled Trial.

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Title: Effect of Preoperative Esketamine Nebulized Inhalation on Cough Reflex, Sedation, and Postoperative Sore Throat in Extubation of Surgical Patients: A Prospective, Double-Blind, Randomized Controlled Trial.
Authors: Zhang ZQ; School of Nursing, Anhui Medical University, Hefei, Anhui, People's Republic of China.; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Yang R; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Li JJ; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Wang J; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Chen SG; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Mei B; Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China., Hu SH; School of Nursing, Anhui Medical University, Hefei, Anhui, People's Republic of China.; Department of Nursing, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Mar 06; Vol. 20, pp. 580872. Date of Electronic Publication: 2026 Mar 06 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1177-8881
DOI:10.2147/DDDT.S580872