ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
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| Title: | ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation. |
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| Authors: | Shah A; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Coria AR; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Membréno BS; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Orgebin E; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Miller JT; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Guiblet W; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Wu CC; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA. colin.wu2@nih.gov. |
| Source: | The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2638-2665. Date of Electronic Publication: 2026 Mar 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-026-00720-4 |
