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ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.

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Title: ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
Authors: Shah A; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Coria AR; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Membréno BS; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Orgebin E; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Miller JT; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA., Guiblet W; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA., Wu CC; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA. colin.wu2@nih.gov.
Source: The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2638-2665. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
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  Data: <searchLink fieldCode="AU" term="%22Shah+A%22">Shah A</searchLink>; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Coria+AR%22">Coria AR</searchLink>; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Membréno+BS%22">Membréno BS</searchLink>; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Orgebin+E%22">Orgebin E</searchLink>; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Miller+JT%22">Miller JT</searchLink>; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Guiblet+W%22">Guiblet W</searchLink>; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research, Frederick, MD, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Wu+CC%22">Wu CC</searchLink>; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, 21702, USA. colin.wu2@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2638-2665. <i>Date of Electronic Publication: </i>2026 Mar 12.
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        Value: 10.1038/s44318-026-00720-4
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