Global prevalence and ethnic variation of pathogenic BRCA1/2 variants in breast cancer: a systematic review and meta-analysis.

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Bibliographic Details
Title: Global prevalence and ethnic variation of pathogenic BRCA1/2 variants in breast cancer: a systematic review and meta-analysis.
Authors: Khan NU; Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, Peshawar, 25130, Pakistan., Lei H; Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, 310022, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310018, China., Fu J; Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, 310022, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310018, China.; Postgraduate Training Base Alliance of Wenzhou Medical University, Zhejiang Cancer Hospital), Wenzhou, 325000, China., Lei R; Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, 310022, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310018, China., Chen X; Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, 310022, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310018, China., Alqarni SS; Department of Clinical Laboratory Science, College of Applied Medical Science, King Saud University, Riyadh, 11421, Saudi Arabia., Chen T; Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, 310022, China. chenth@zjcc.org.cn.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310018, China. chenth@zjcc.org.cn.
Source: Journal of translational medicine [J Transl Med] 2026 Mar 12; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 12.
Publication Type: Systematic Review; Journal Article; Meta-Analysis
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1479-5876
DOI:10.1186/s12967-026-07997-3