Polygenic score for C-reactive protein is linked to faster cortical thinning and psychopathology risk in adolescents.

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Title: Polygenic score for C-reactive protein is linked to faster cortical thinning and psychopathology risk in adolescents.
Authors: Zheng H; Laureate Institute for Brain Research, Tulsa, OK USA.; Oxley College of Health and Natural Sciences, The University of Tulsa, Tulsa, OK USA., Savitz J; Laureate Institute for Brain Research, Tulsa, OK USA.; Oxley College of Health and Natural Sciences, The University of Tulsa, Tulsa, OK USA., Haroon E; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA USA., Ahern J; Center for Population Neuroscience and Genetics, Tulsa, OK USA.; Department of Cognitive Science, University of California, San Diego, La Jolla, CA USA., Loughnan RJ; Center for Population Neuroscience and Genetics, Tulsa, OK USA.; J. Craig Venter Institute, La Jolla, CA USA., Naber F; Laureate Institute for Brain Research, Tulsa, OK USA., Xu B; Laureate Institute for Brain Research, Tulsa, OK USA.; Center for Population Neuroscience and Genetics, Tulsa, OK USA., Forthman KL; Laureate Institute for Brain Research, Tulsa, OK USA., Aupperle RL; Laureate Institute for Brain Research, Tulsa, OK USA.; Oxley College of Health and Natural Sciences, The University of Tulsa, Tulsa, OK USA., Williams LM; Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA USA., Paulus MP; Laureate Institute for Brain Research, Tulsa, OK USA.; Oxley College of Health and Natural Sciences, The University of Tulsa, Tulsa, OK USA., Fan CC; Laureate Institute for Brain Research, Tulsa, OK USA.; Center for Population Neuroscience and Genetics, Tulsa, OK USA.; Department of Radiology, University of California School of Medicine, San Diego, CA USA., Thompson WK; Laureate Institute for Brain Research, Tulsa, OK USA.; Center for Population Neuroscience and Genetics, Tulsa, OK USA.
Source: Nature. Mental health [Nat Ment Health] 2026; Vol. 4 (3), pp. 427-438. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918486688806676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-6076 (Electronic) Linking ISSN: 27316076 NLM ISO Abbreviation: Nat Ment Health Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2731-6076
DOI:10.1038/s44220-026-00585-w