Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in cutaneous squamous cell carcinoma.

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Title: Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in cutaneous squamous cell carcinoma.
Authors: Shen AS; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA., Anand S; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Department of Biomedical Engineering, Cleveland Clinic Research Institute, Cleveland, OH, USA.; Department of Dermatology, Medical Specialty Institute, Cleveland Clinic, Cleveland, OH, USA., Cheng CE; Department of Biomedical Engineering, Cleveland Clinic Research Institute, Cleveland, OH, USA., Kovacic B; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA., Powers J; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA., Diaz-Montero CM; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA., Hasan T; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA., Maytin EV; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA. maytine@ccf.org.; Department of Biomedical Engineering, Cleveland Clinic Research Institute, Cleveland, OH, USA. maytine@ccf.org.; Department of Dermatology, Medical Specialty Institute, Cleveland Clinic, Cleveland, OH, USA. maytine@ccf.org.; Cleveland Clinic Research, Cleveland Clinic, 9500 Euclid Avenue, Mailstop ND-20, Cleveland, OH, 44195, USA. maytine@ccf.org.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Mar 14; Vol. 75 (4). Date of Electronic Publication: 2026 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in cutaneous squamous cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Shen+AS%22">Shen AS</searchLink>; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Anand+S%22">Anand S</searchLink>; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Department of Biomedical Engineering, Cleveland Clinic Research Institute, Cleveland, OH, USA.; Department of Dermatology, Medical Specialty Institute, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+CE%22">Cheng CE</searchLink>; Department of Biomedical Engineering, Cleveland Clinic Research Institute, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Kovacic+B%22">Kovacic B</searchLink>; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Powers+J%22">Powers J</searchLink>; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Diaz-Montero+CM%22">Diaz-Montero CM</searchLink>; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Hasan+T%22">Hasan T</searchLink>; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Maytin+EV%22">Maytin EV</searchLink>; Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA. maytine@ccf.org.; Department of Biomedical Engineering, Cleveland Clinic Research Institute, Cleveland, OH, USA. maytine@ccf.org.; Department of Dermatology, Medical Specialty Institute, Cleveland Clinic, Cleveland, OH, USA. maytine@ccf.org.; Cleveland Clinic Research, Cleveland Clinic, 9500 Euclid Avenue, Mailstop ND-20, Cleveland, OH, 44195, USA. maytine@ccf.org.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00262-026-04347-6
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        Text: English
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      – TitleFull: Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in cutaneous squamous cell carcinoma.
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              Text: 2026 Mar 14
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              Y: 2026
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