Cell Painting reveals polypharmacological activity on the V-ATPase by the F-ATPase inhibitor Cyhexatin.

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Title: Cell Painting reveals polypharmacological activity on the V-ATPase by the F-ATPase inhibitor Cyhexatin.
Authors: Hecker FA; University Bielefeld, Proteome and Metabolome Research, Bielefeld, Germany., Grohs M; R&D Hit Discovery, Bayer AG, Crop Science Division, Monheim, Germany., Koenig T; R&D Image-based Screening Systems, Bayer AG, Pharma Division, Wuppertal, Germany., Niehaus K; University Bielefeld, Proteome and Metabolome Research, Bielefeld, Germany., Gnutt D; R&D Image-based Screening Systems, Bayer AG, Pharma Division, Wuppertal, Germany., Geibel S; R&D Hit Discovery, Bayer AG, Crop Science Division, Monheim, Germany. Electronic address: sven.geibel@bayer.com.
Source: Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2026 Apr; Vol. 219, pp. 106978. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1095-9939
DOI:10.1016/j.pestbp.2026.106978