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Cell Painting reveals polypharmacological activity on the V-ATPase by the F-ATPase inhibitor Cyhexatin.

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Title: Cell Painting reveals polypharmacological activity on the V-ATPase by the F-ATPase inhibitor Cyhexatin.
Authors: Hecker FA; University Bielefeld, Proteome and Metabolome Research, Bielefeld, Germany., Grohs M; R&D Hit Discovery, Bayer AG, Crop Science Division, Monheim, Germany., Koenig T; R&D Image-based Screening Systems, Bayer AG, Pharma Division, Wuppertal, Germany., Niehaus K; University Bielefeld, Proteome and Metabolome Research, Bielefeld, Germany., Gnutt D; R&D Image-based Screening Systems, Bayer AG, Pharma Division, Wuppertal, Germany., Geibel S; R&D Hit Discovery, Bayer AG, Crop Science Division, Monheim, Germany. Electronic address: sven.geibel@bayer.com.
Source: Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2026 Apr; Vol. 219, pp. 106978. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Cell Painting reveals polypharmacological activity on the V-ATPase by the F-ATPase inhibitor Cyhexatin.
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  Data: <searchLink fieldCode="AU" term="%22Hecker+FA%22">Hecker FA</searchLink>; University Bielefeld, Proteome and Metabolome Research, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Grohs+M%22">Grohs M</searchLink>; R&D Hit Discovery, Bayer AG, Crop Science Division, Monheim, Germany.<br /><searchLink fieldCode="AU" term="%22Koenig+T%22">Koenig T</searchLink>; R&D Image-based Screening Systems, Bayer AG, Pharma Division, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Niehaus+K%22">Niehaus K</searchLink>; University Bielefeld, Proteome and Metabolome Research, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Gnutt+D%22">Gnutt D</searchLink>; R&D Image-based Screening Systems, Bayer AG, Pharma Division, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Geibel+S%22">Geibel S</searchLink>; R&D Hit Discovery, Bayer AG, Crop Science Division, Monheim, Germany. Electronic address: sven.geibel@bayer.com.
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  Data: <searchLink fieldCode="JN" term="%221301573%22">Pesticide biochemistry and physiology</searchLink> [Pestic Biochem Physiol] 2026 Apr; Vol. 219, pp. 106978. <i>Date of Electronic Publication: </i>2026 Jan 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1301573 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9939 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200483575%22">00483575 </searchLink><i>NLM ISO Abbreviation: </i>Pestic Biochem Physiol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.pestbp.2026.106978
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              Text: 2026 Apr
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