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Novel Pediatric Aggressive Adipose Tumor With Pathogenic TERT Promoter Variant and an Initial Durable Response to Vincristine and Dactinomycin.

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Title: Novel Pediatric Aggressive Adipose Tumor With Pathogenic TERT Promoter Variant and an Initial Durable Response to Vincristine and Dactinomycin.
Authors: Hare L; Department of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Department of Paediatric Oncology, Birmingham Children's Hospital, Birmingham, UK., Hughes J; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Morgan M; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Burke GAA; Department of Paediatric Oncology, Birmingham Children's Hospital, Birmingham, UK.; Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK., Trotman J; East Genomic Laboratory Hub (GLH) Genetics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Tarpey P; East Genomic Laboratory Hub (GLH) Genetics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hatcher H; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Ford SJ; Department of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Midlands Abdominal and Retroperitoneal Sarcoma Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Watkins AJ; East Genomic Laboratory Hub (GLH) Genetics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hook CE; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Murray MJ; Department of Pathology, University of Cambridge, Cambridge, UK.; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2026 May; Vol. 73 (5), pp. e70193. Date of Electronic Publication: 2026 Mar 15.
Publication Type: Letter
Journal Info: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Novel Pediatric Aggressive Adipose Tumor With Pathogenic TERT Promoter Variant and an Initial Durable Response to Vincristine and Dactinomycin.
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  Data: <searchLink fieldCode="AU" term="%22Hare+L%22">Hare L</searchLink>; Department of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Department of Paediatric Oncology, Birmingham Children's Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Hughes+J%22">Hughes J</searchLink>; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+M%22">Morgan M</searchLink>; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Burke+GAA%22">Burke GAA</searchLink>; Department of Paediatric Oncology, Birmingham Children's Hospital, Birmingham, UK.; Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Trotman+J%22">Trotman J</searchLink>; East Genomic Laboratory Hub (GLH) Genetics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tarpey+P%22">Tarpey P</searchLink>; East Genomic Laboratory Hub (GLH) Genetics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hatcher+H%22">Hatcher H</searchLink>; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ford+SJ%22">Ford SJ</searchLink>; Department of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.; Midlands Abdominal and Retroperitoneal Sarcoma Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Watkins+AJ%22">Watkins AJ</searchLink>; East Genomic Laboratory Hub (GLH) Genetics Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hook+CE%22">Hook CE</searchLink>; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Murray+MJ%22">Murray MJ</searchLink>; Department of Pathology, University of Cambridge, Cambridge, UK.; Department of Paediatric Haematology and Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
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  Data: <searchLink fieldCode="JN" term="%22101186624%22">Pediatric blood & cancer</searchLink> [Pediatr Blood Cancer] 2026 May; Vol. 73 (5), pp. e70193. <i>Date of Electronic Publication: </i>2026 Mar 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley%22">John Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101186624 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-5017 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215455009%22">15455009 </searchLink><i>NLM ISO Abbreviation: </i>Pediatr Blood Cancer <i>Subsets: </i>MEDLINE; In Process
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41834419
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        Value: 10.1002/1545-5017.70193
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            – D: 01
              M: 05
              Text: 2026 May
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