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Microfluidic nanomagnetically isolated neuron- and astrocyte-derived extracellular vesicles to differentiate Lewy body and Alzheimer's disease.

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Title: Microfluidic nanomagnetically isolated neuron- and astrocyte-derived extracellular vesicles to differentiate Lewy body and Alzheimer's disease.
Authors: Yang SJ; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA., Lin AA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Shen H; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA., Pappalardo LW; Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA USA., Spychalski GB; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA., Rosario J; Department of Biology, University of Pennsylvania, Philadelphia, PA USA., Forsberg LK; Department of Neurology, Mayo Clinic, Rochester, MN USA., Grant KM; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN USA., Buser JR; Consonant Systems, LLC, Philadelphia, PA USA., Savica R; Department of Neurology, Mayo Clinic, Rochester, MN USA., O'Bryant S; Health Science Center at Fort Worth, University of North Texas, Fort Worth, TX USA., Jones DT; Department of Neurology, Mayo Clinic, Rochester, MN USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL USA., Reichard RR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN USA., Nguyen AT; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN USA., Meaney DF; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN USA., Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL USA., McLean PJ; Department of Neuroscience, Mayo Clinic, Jacksonville, FL USA., Issadore D; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.
Source: Npj biosensing [NPJ Biosens] 2026; Vol. 3 (1), pp. 19. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918900941706676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 3004-8656 (Electronic) Linking ISSN: 30048656 NLM ISO Abbreviation: NPJ Biosens Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Microfluidic nanomagnetically isolated neuron- and astrocyte-derived extracellular vesicles to differentiate Lewy body and Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Yang+SJ%22">Yang SJ</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Lin+AA%22">Lin AA</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Shen+H%22">Shen H</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Pappalardo+LW%22">Pappalardo LW</searchLink>; Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Spychalski+GB%22">Spychalski GB</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Rosario+J%22">Rosario J</searchLink>; Department of Biology, University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Forsberg+LK%22">Forsberg LK</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22Grant+KM%22">Grant KM</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22Buser+JR%22">Buser JR</searchLink>; Consonant Systems, LLC, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Savica+R%22">Savica R</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22O'Bryant+S%22">O'Bryant S</searchLink>; Health Science Center at Fort Worth, University of North Texas, Fort Worth, TX USA.<br /><searchLink fieldCode="AU" term="%22Jones+DT%22">Jones DT</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22Dickson+DW%22">Dickson DW</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL USA.<br /><searchLink fieldCode="AU" term="%22Reichard+RR%22">Reichard RR</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+AT%22">Nguyen AT</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22Meaney+DF%22">Meaney DF</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.<br /><searchLink fieldCode="AU" term="%22Boeve+BF%22">Boeve BF</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN USA.<br /><searchLink fieldCode="AU" term="%22Ross+OA%22">Ross OA</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL USA.<br /><searchLink fieldCode="AU" term="%22McLean+PJ%22">McLean PJ</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL USA.<br /><searchLink fieldCode="AU" term="%22Issadore+D%22">Issadore D</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA USA.
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  Data: <searchLink fieldCode="JN" term="%229918900941706676%22">Npj biosensing</searchLink> [NPJ Biosens] 2026; Vol. 3 (1), pp. 19. <i>Date of Electronic Publication: </i>2026 Mar 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918900941706676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>3004-8656 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2230048656%22">30048656 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Biosens <i>Subsets: </i>PubMed not MEDLINE
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