Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.

Saved in:
Bibliographic Details
Title: Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.
Authors: Hu Z; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China., Yin Z; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany., Lu G; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China., Luo Q; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China., He X; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Zhan L; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Goldfuss B; Department for Chemistry, Institute of Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany., Xu J; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China., Bian G; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Dickschat JS; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2026 Mar 25; Vol. 148 (11), pp. 12377-12386. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41837705
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Hu+Z%22">Hu Z</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China.<br /><searchLink fieldCode="AU" term="%22Yin+Z%22">Yin Z</searchLink>; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany.<br /><searchLink fieldCode="AU" term="%22Lu+G%22">Lu G</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.<br /><searchLink fieldCode="AU" term="%22Luo+Q%22">Luo Q</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.<br /><searchLink fieldCode="AU" term="%22He+X%22">He X</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Zhan+L%22">Zhan L</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Goldfuss+B%22">Goldfuss B</searchLink>; Department for Chemistry, Institute of Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China.<br /><searchLink fieldCode="AU" term="%22Bian+G%22">Bian G</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Dickschat+JS%22">Dickschat JS</searchLink>; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%227503056%22">Journal of the American Chemical Society</searchLink> [J Am Chem Soc] 2026 Mar 25; Vol. 148 (11), pp. 12377-12386. <i>Date of Electronic Publication: </i>2026 Mar 16.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7503056 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5126 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200027863%22">00027863 </searchLink><i>NLM ISO Abbreviation: </i>J Am Chem Soc <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41837705
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/jacs.6c02649
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 12377
    Titles:
      – TitleFull: Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hu Z
      – PersonEntity:
          Name:
            NameFull: Yin Z
      – PersonEntity:
          Name:
            NameFull: Lu G
      – PersonEntity:
          Name:
            NameFull: Luo Q
      – PersonEntity:
          Name:
            NameFull: He X
      – PersonEntity:
          Name:
            NameFull: Zhan L
      – PersonEntity:
          Name:
            NameFull: Goldfuss B
      – PersonEntity:
          Name:
            NameFull: Xu J
      – PersonEntity:
          Name:
            NameFull: Bian G
      – PersonEntity:
          Name:
            NameFull: Dickschat JS
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 25
              M: 03
              Text: 2026 Mar 25
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1520-5126
          Numbering:
            – Type: volume
              Value: 148
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Journal of the American Chemical Society
              Type: main
ResultId 1