Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS.
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| Title: | Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS. |
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| Authors: | Hu Z; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China., Yin Z; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany., Lu G; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China., Luo Q; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China., He X; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Zhan L; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Goldfuss B; Department for Chemistry, Institute of Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany., Xu J; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China., Bian G; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China., Dickschat JS; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany. |
| Source: | Journal of the American Chemical Society [J Am Chem Soc] 2026 Mar 25; Vol. 148 (11), pp. 12377-12386. Date of Electronic Publication: 2026 Mar 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41837705 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hu+Z%22">Hu Z</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China.<br /><searchLink fieldCode="AU" term="%22Yin+Z%22">Yin Z</searchLink>; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany.<br /><searchLink fieldCode="AU" term="%22Lu+G%22">Lu G</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.<br /><searchLink fieldCode="AU" term="%22Luo+Q%22">Luo Q</searchLink>; Guangdong Provincial Key Laboratory of Chinese Medicine Pharmaceutics, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.<br /><searchLink fieldCode="AU" term="%22He+X%22">He X</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Zhan+L%22">Zhan L</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Goldfuss+B%22">Goldfuss B</searchLink>; Department for Chemistry, Institute of Organic Chemistry, University of Cologne, Greinstraße 4, 50939 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry, Huazhong Agricultural University, Hubei Hongshan Laboratory, Wuhan 430070, China.<br /><searchLink fieldCode="AU" term="%22Bian+G%22">Bian G</searchLink>; State Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Center of Materials Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Dickschat+JS%22">Dickschat JS</searchLink>; Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, Gerhard-Domagk-Straße 1, Bonn 53121, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227503056%22">Journal of the American Chemical Society</searchLink> [J Am Chem Soc] 2026 Mar 25; Vol. 148 (11), pp. 12377-12386. <i>Date of Electronic Publication: </i>2026 Mar 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7503056 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5126 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200027863%22">00027863 </searchLink><i>NLM ISO Abbreviation: </i>J Am Chem Soc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41837705 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/jacs.6c02649 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 12377 Titles: – TitleFull: Systematic Discovery of Bacterial Diterpene Synthases and Structure-Guided Functional Interconversion of ShHS and CbCS. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hu Z – PersonEntity: Name: NameFull: Yin Z – PersonEntity: Name: NameFull: Lu G – PersonEntity: Name: NameFull: Luo Q – PersonEntity: Name: NameFull: He X – PersonEntity: Name: NameFull: Zhan L – PersonEntity: Name: NameFull: Goldfuss B – PersonEntity: Name: NameFull: Xu J – PersonEntity: Name: NameFull: Bian G – PersonEntity: Name: NameFull: Dickschat JS IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 03 Text: 2026 Mar 25 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1520-5126 Numbering: – Type: volume Value: 148 – Type: issue Value: 11 Titles: – TitleFull: Journal of the American Chemical Society Type: main |
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