Fine-tuning ERK activity enables proliferation-differentiation balance during lineage specification of human embryonic stem cells.
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| Title: | Fine-tuning ERK activity enables proliferation-differentiation balance during lineage specification of human embryonic stem cells. |
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| Authors: | Ma C; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China., Meng W; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China., Huang J; Institute of Natural Sciences, Shanghai Jiao Tong University, Shanghai, China.; School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China., Zheng W; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China.; Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Xu X; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China., Cheng T; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China.; Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Li Z; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China., Liu Y; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China., Shen H; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China., He F; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China.; Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Esposito A; Centre for Genome Engineering and Maintenance, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Xu P; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China.; Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Venkitaraman A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; NUS Centre for Cancer Research (N2CR), National University of Singapore, Singapore, Singapore., Ma J; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China.; Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Xu H; Institute of Natural Sciences, Shanghai Jiao Tong University, Shanghai, China.; School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, China., Liang H; Division of Human Reproduction and Developmental Genetics, Key Laboratory of Reproductive Genetics (Ministry of Education), Women's Hospital, and School of Medicine, Zhejiang University, Hangzhou, China.; Institute of Genetics, Zhejiang University International School of Medicine, Hangzhou, China. |
| Source: | PLoS biology [PLoS Biol] 2026 Mar 17; Vol. 24 (3), pp. e3003711. Date of Electronic Publication: 2026 Mar 17 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1545-7885 |
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| DOI: | 10.1371/journal.pbio.3003711 |
