Single-cell epigenetic landscape, microenvironment interactions, and gene regulatory modules of non-functioning pituitary adenomas.

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Title: Single-cell epigenetic landscape, microenvironment interactions, and gene regulatory modules of non-functioning pituitary adenomas.
Authors: Zhang Z; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Cheng WS; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Taniguchi-Ponciano K; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Marrero-Rodríguez D; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Smith GR; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Pincas H; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Sagendorf TJ; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA., Mendelev N; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Strupinsky G; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ge Y; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Zamojski M; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Chen X; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08540, USA., Amper MAS; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Park CY; Center for Computational Biology, Flatiron Institute, New York, NY 10010, USA., Nair VD; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Andoniadou CL; Centre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK; Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Turgeon JL; Department of Internal Medicine, University of California, Davis, Davis, CA, USA., Zaslavsky E; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Troyanskaya OG; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08540, USA; Center for Computational Biology, Flatiron Institute, New York, NY 10010, USA; Department of Computer Science, Princeton University, Princeton, NJ 08540, USA., Mercado M; Unidad de Investigación Médica en Enfermedades Endocrinas, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Sealfon SC; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: stuart.sealfon@mssm.edu., Ruf-Zamojski F; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: frederique.ruf-zamojski@csmc.edu.
Source: Cell systems [Cell Syst] 2026 Apr 15; Vol. 17 (4), pp. 101532. Date of Electronic Publication: 2026 Mar 16.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101656080 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4720 (Electronic) Linking ISSN: 24054712 NLM ISO Abbreviation: Cell Syst Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2405-4720
DOI:10.1016/j.cels.2026.101532