Loss of PRKACB facilitates metastasis of diffuse-type gastric cancer through RhoA signaling activation.
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| Title: | Loss of PRKACB facilitates metastasis of diffuse-type gastric cancer through RhoA signaling activation. |
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| Authors: | Sun J; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Zhao J; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of General Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian, China., Yang X; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Tian C; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Ji C; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Liu J; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China., Nomura S; Department of Pathology, Nippon Veterinary and Life Science University, Tokyo, Japan., Ruan Y; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China. ryyfdu@126.com.; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China. ryyfdu@126.com., Wang X; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China. wang.xuefei@zs-hospital.sh.cn.; Department of General Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian, China. wang.xuefei@zs-hospital.sh.cn.; Clinical Research Center for Precision Medicine of Abdominal Tumor of Fujian Province, Xiamen, Fujian, China. wang.xuefei@zs-hospital.sh.cn., Li H; Department of Gastrointestinal Surgery, Zhongshan Hospital, Fudan University; Cancer Center, Zhongshan Hospital, Fudan University; Gastric Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China. li.haojie@zs-hospital.sh.cn.; Department of General Surgery, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian, China. li.haojie@zs-hospital.sh.cn. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Mar 18; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-026-08553-z |
