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RPA directly stimulates Mer3 helicase processivity to ensure normal crossover formation in meiosis.

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Title: RPA directly stimulates Mer3 helicase processivity to ensure normal crossover formation in meiosis.
Authors: Altmannova V; Structural Biochemistry of Meiosis Group, Friedrich Miescher Laboratory, Tübingen, Germany., Orlić L; University of Vienna, Max Perutz Labs, Vienna, Austria.; Vienna Biocenter PhD Program, a Doctoral School of the University of Vienna and the Medical University of Vienna, Vienna, Austria.; Max Perutz Labs, Vienna BioCenter (VBC), Vienna, Austria., Carrasco C; Centro Nacional de Biotecnologia, CSIC, Madrid, Spain., Adam C; Institut Curie, PSL University, Sorbonne Université, CNRS UMR3244, Dynamics of Genetic Information, Paris, France., Aicart-Ramos C; Centro Nacional de Biotecnologia, CSIC, Madrid, Spain., Guerrini D; Structural Biochemistry of Meiosis Group, Friedrich Miescher Laboratory, Tübingen, Germany., Janning P; Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany., Borde V; Institut Curie, PSL University, Sorbonne Université, CNRS UMR3244, Dynamics of Genetic Information, Paris, France., Matos J; University of Vienna, Max Perutz Labs, Vienna, Austria.; Max Perutz Labs, Vienna BioCenter (VBC), Vienna, Austria., Moreno-Herrero F; Centro Nacional de Biotecnologia, CSIC, Madrid, Spain., Weir JR; Structural Biochemistry of Meiosis Group, Friedrich Miescher Laboratory, Tübingen, Germany. john.weir@tuebingen.mpg.de.
Source: Nature communications [Nat Commun] 2026 Mar 18; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-026-69985-x