The AICL-KLRF1 axis supports CD4-CD8 T cell communication and cytokine competence in pre-exhausted CD8+ T cells.
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| Title: | The AICL-KLRF1 axis supports CD4-CD8 T cell communication and cytokine competence in pre-exhausted CD8+ T cells. |
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| Authors: | Barone M; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Peidli S; Institute of Pathology, Charité, Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Biology, Humbolt-Universität zu Berlin, Berlin, Germany., Neuschulz A; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Riesterer K; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Iwert C; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Junquera L; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Sai S; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Bolaji O; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Bakoueva D; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Appelt C; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Obermayer B; Core Unit Bioinformatics (CUBI), Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Klinger B; Institute of Pathology, Charité, Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Biology, Humbolt-Universität zu Berlin, Berlin, Germany., Trinks A; Bioportal Single Cells, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117, Berlin, Germany., Sieber A; Institute of Pathology, Charité, Charité Universitätsmedizin Berlin, Berlin, Germany., Blüthgen N; Institute of Pathology, Charité, Charité Universitätsmedizin Berlin, Berlin, Germany.; Institute of Biology, Humbolt-Universität zu Berlin, Berlin, Germany., Sawitzki B; Berlin Institute of Health (BIH) at Charité, Charité Universitätsmedizin Berlin, Berlin, Germany. birgit.sawitzki@bih-charite.de.; Der Simulierte Mensch, a science framework of Technische Universität Berlin and Charité - Universitätsmedizin Berlin, Berlin, Germany. birgit.sawitzki@bih-charite.de. |
| Source: | EMBO reports [EMBO Rep] 2026 Apr; Vol. 27 (8), pp. 2029-2060. Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1469-3178 |
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| DOI: | 10.1038/s44319-026-00732-5 |
