The medial orbitofrontal cortex mediates neuropathic pain and anxiodepressive-like behaviors via two distinct pathways.

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Title: The medial orbitofrontal cortex mediates neuropathic pain and anxiodepressive-like behaviors via two distinct pathways.
Authors: Li Z; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Si T; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Gao L; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Meng Y; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Su X; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Tao L; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Zhang J; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Hu Z; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Ge Y; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Meng X; Emergency Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. doctormeng2015@163.com., Cao J; Department of Anatomy, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China. caojing@zzu.edu.cn.
Source: The journal of headache and pain [J Headache Pain] 2026 Mar 18; Vol. 27 (1). Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1129-2377
DOI:10.1186/s10194-026-02335-w