Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond.
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| Title: | Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond. |
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| Authors: | Cheung A; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Liu Y; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Chenoweth AM; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Montaseri H; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Esapa B; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Chudasama V; Department of Chemistry, University College London, London, United Kingdom., Baker JR; Department of Chemistry, University College London, London, United Kingdom., Thurston DE; Institute of Pharmaceutical Science, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom., Karagiannis SN; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom. |
| Source: | Physiological reviews [Physiol Rev] 2026 Jul 01; Vol. 106 (3), pp. 1681-1756. Date of Electronic Publication: 2026 Mar 19. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 0231714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1210 (Electronic) Linking ISSN: 00319333 NLM ISO Abbreviation: Physiol Rev Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1210 |
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| DOI: | 10.1152/physrev.00039.2025 |
