Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond.
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| Title: | Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond. |
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| Authors: | Cheung A; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Liu Y; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Chenoweth AM; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Montaseri H; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Esapa B; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom., Chudasama V; Department of Chemistry, University College London, London, United Kingdom., Baker JR; Department of Chemistry, University College London, London, United Kingdom., Thurston DE; Institute of Pharmaceutical Science, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom., Karagiannis SN; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom. |
| Source: | Physiological reviews [Physiol Rev] 2026 Jul 01; Vol. 106 (3), pp. 1681-1756. Date of Electronic Publication: 2026 Mar 19. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 0231714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1210 (Electronic) Linking ISSN: 00319333 NLM ISO Abbreviation: Physiol Rev Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41855081 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cheung+A%22">Cheung A</searchLink>; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chenoweth+AM%22">Chenoweth AM</searchLink>; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Montaseri+H%22">Montaseri H</searchLink>; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Esapa+B%22">Esapa B</searchLink>; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chudasama+V%22">Chudasama V</searchLink>; Department of Chemistry, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Baker+JR%22">Baker JR</searchLink>; Department of Chemistry, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Thurston+DE%22">Thurston DE</searchLink>; Institute of Pharmaceutical Science, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Karagiannis+SN%22">Karagiannis SN</searchLink>; Breast Cancer Now Research Unit, School of Cancer and Pharmaceutical Sciences, King's College London, Innovation Hub, Guy's Hospital, London, United Kingdom.; St. John's Institute of Dermatology, School of Basic and Medical Biosciences and King's Health Partners Centre for Translational Medicine, Guy's Hospital, King's College London, London, United Kingdom. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220231714%22">Physiological reviews</searchLink> [Physiol Rev] 2026 Jul 01; Vol. 106 (3), pp. 1681-1756. <i>Date of Electronic Publication: </i>2026 Mar 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Review – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Physiological+Society%22">American Physiological Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0231714 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-1210 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200319333%22">00319333 </searchLink><i>NLM ISO Abbreviation: </i>Physiol Rev <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41855081 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1152/physrev.00039.2025 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1681 Titles: – TitleFull: Antibody-drug conjugate design and mechanisms of action for cancer treatment: state of the art and beyond. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cheung A – PersonEntity: Name: NameFull: Liu Y – PersonEntity: Name: NameFull: Chenoweth AM – PersonEntity: Name: NameFull: Montaseri H – PersonEntity: Name: NameFull: Esapa B – PersonEntity: Name: NameFull: Chudasama V – PersonEntity: Name: NameFull: Baker JR – PersonEntity: Name: NameFull: Thurston DE – PersonEntity: Name: NameFull: Karagiannis SN IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1522-1210 Numbering: – Type: volume Value: 106 – Type: issue Value: 3 Titles: – TitleFull: Physiological reviews Type: main |
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