The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets.

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Title: The JMJD family histone demethylases: structure, mechanism of action, diseases and therapeutic targets.
Authors: Hong Y; Xiamen Key Laboratory of Traditional Chinese Medicine Bio-Engineering, School of Pharmacy, Xiamen Medical College, Xiamen, Fujian, 361023, China., Guo H; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, 361104, China., Chen Q; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Ningbo University, Ningbo, Zhejiang, 315211, China. chenqiang1@nbu.edu.cn.; Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Affiliated First Hospital of Ningbo University, Ningbo, Zhejiang, 315010, China. chenqiang1@nbu.edu.cn., Yu C; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, 361104, China. cdyu@xmu.edu.cn.; School of Life Sciences, Xiamen University, Xiamen, Fujian, 361102, China. cdyu@xmu.edu.cn.
Source: Molecular biomedicine [Mol Biomed] 2026 Mar 20; Vol. 7 (1). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2662-8651
DOI:10.1186/s43556-026-00434-3