Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients.

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Title: Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients.
Authors: Lim JS; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju-si, South Korea., Wu CY; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Qin Z; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Liu CJ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., van Rooyen D; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Sapiro DR; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Giordano TJ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Turcu AF; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Rainey WE; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Udager AM; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. udager@umich.edu.
Source: Endocrine pathology [Endocr Pathol] 2026 Mar 20; Vol. 37 (1). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9009288 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0097 (Electronic) Linking ISSN: 10463976 NLM ISO Abbreviation: Endocr Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1559-0097
DOI:10.1007/s12022-026-09912-4