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Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients.

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Title: Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients.
Authors: Lim JS; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju-si, South Korea., Wu CY; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Qin Z; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Liu CJ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., van Rooyen D; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Sapiro DR; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Giordano TJ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Turcu AF; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Rainey WE; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Udager AM; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. udager@umich.edu.
Source: Endocrine pathology [Endocr Pathol] 2026 Mar 20; Vol. 37 (1). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9009288 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-0097 (Electronic) Linking ISSN: 10463976 NLM ISO Abbreviation: Endocr Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients.
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  Data: <searchLink fieldCode="AU" term="%22Lim+JS%22">Lim JS</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju-si, South Korea.<br /><searchLink fieldCode="AU" term="%22Wu+CY%22">Wu CY</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Qin+Z%22">Qin Z</searchLink>; Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Liu+CJ%22">Liu CJ</searchLink>; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22van+Rooyen+D%22">van Rooyen D</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Sapiro+DR%22">Sapiro DR</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Giordano+TJ%22">Giordano TJ</searchLink>; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Turcu+AF%22">Turcu AF</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Rainey+WE%22">Rainey WE</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Udager+AM%22">Udager AM</searchLink>; Department of Pathology, University of Michigan, Ann Arbor, MI, USA. udager@umich.edu.
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  Data: <searchLink fieldCode="JN" term="%229009288%22">Endocrine pathology</searchLink> [Endocr Pathol] 2026 Mar 20; Vol. 37 (1). <i>Date of Electronic Publication: </i>2026 Mar 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Humana+Press%22">Humana Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9009288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-0097 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210463976%22">10463976 </searchLink><i>NLM ISO Abbreviation: </i>Endocr Pathol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12022-026-09912-4
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        Text: English
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      – TitleFull: Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients.
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              Text: 2026 Mar 20
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