Panx3 deficiency in mice impairs bone fracture healing and causes transient hypoglycemia in neonatal animals.

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Title: Panx3 deficiency in mice impairs bone fracture healing and causes transient hypoglycemia in neonatal animals.
Authors: Jiang S; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., Baranowsky A; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., Luther J; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., O'Donnell BL; Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada., Wakefield B; Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada., Bassen C; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., Neven M; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., Eis-Janzyk G; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., Amling M; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany., Penuela S; Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada., Schinke T; Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany. schinke@uke.de., Keller J; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, 20251, Germany. j.keller@uke.de.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 Mar 19; Vol. 32 (1). Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1528-3658
DOI:10.1186/s10020-026-01458-9