TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination.
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| Title: | TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination. |
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| Authors: | Zhang S; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, China.; Taizhou School of Clinical Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, 366 Taihu Road, Taizhou, Jiangsu, 225300, China., Wang Z; Department of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Cheng R; Department of Ultrasound Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 31000, China., Yang X; Department of Neurology, Dazhou Central Hospital, Dazhou, Sichuan, 635099, China., Jiang A; Department of Rehabilitation Medicine, Key Laboratory of Physical Medicine and Precision Rehabilitation of Chongqing Municipal Health Commission, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Zhu L; Taizhou School of Clinical Medicine, The Affiliated Taizhou People's Hospital of Nanjing Medical University, 366 Taihu Road, Taizhou, Jiangsu, 225300, China. zhuli@njmu.edu.cn., Qin X; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400016, China. qinxinyuecqmu@163.com. |
| Source: | Journal of neuroinflammation [J Neuroinflammation] 2026 Mar 19; Vol. 23 (1). Date of Electronic Publication: 2026 Mar 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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