ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.

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Title: ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
Authors: Zhao Y; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Zhang Y; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Lei T; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Zhang S; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Nan K; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, P.R. China., Zhang X; Department of Orthopedics, The Second Affiliated Hospital of Air Force Medical University, Xi'an, Shaanxi 710038, P.R. China., Fan LH; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.
Source: International journal of molecular medicine [Int J Mol Med] 2026 May; Vol. 57 (5). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1791-244X
DOI:10.3892/ijmm.2026.5805