ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.

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Title: ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
Authors: Zhao Y; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Zhang Y; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Lei T; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Zhang S; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China., Nan K; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, P.R. China., Zhang X; Department of Orthopedics, The Second Affiliated Hospital of Air Force Medical University, Xi'an, Shaanxi 710038, P.R. China., Fan LH; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.
Source: International journal of molecular medicine [Int J Mol Med] 2026 May; Vol. 57 (5). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lei+T%22">Lei T</searchLink>; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.<br /><searchLink fieldCode="AU" term="%22Nan+K%22">Nan K</searchLink>; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Orthopedics, The Second Affiliated Hospital of Air Force Medical University, Xi'an, Shaanxi 710038, P.R. China.<br /><searchLink fieldCode="AU" term="%22Fan+LH%22">Fan LH</searchLink>; Department of Sports Medicine, Orthopedic Center, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China.
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  Data: <searchLink fieldCode="JN" term="%229810955%22">International journal of molecular medicine</searchLink> [Int J Mol Med] 2026 May; Vol. 57 (5). <i>Date of Electronic Publication: </i>2026 Mar 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22D%2EA%2E+Spandidos%22">D.A. Spandidos </searchLink><i>Country of Publication: </i>Greece <i>NLM ID: </i>9810955 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1791-244X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211073756%22">11073756 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Med <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.3892/ijmm.2026.5805
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        Text: English
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      – TitleFull: ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.
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              Text: 2026 May
              Type: published
              Y: 2026
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