Retroviral intasome architecture shapes the dynamics of target DNA search and integration.

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Title: Retroviral intasome architecture shapes the dynamics of target DNA search and integration.
Authors: Baltierra-Jasso LE; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America.; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, United States of America., Larue RC; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, United States of America., Jones ND; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America., Tan YY; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America., Messer R; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America., Ballandras-Colas A; Institut de Biologie Structurale, University Grenoble Alpes, CNRS, CEA, Grenoble, France., Engelman AN; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America., Fishel R; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America., Yoder KE; Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, Ohio, United States of America.; Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America.; Center for Retrovirus Research, The Ohio State University, Columbus, Ohio, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2026 Mar 20; Vol. 22 (3), pp. e1014070. Date of Electronic Publication: 2026 Mar 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7374
DOI:10.1371/journal.ppat.1014070