TSP-1 interaction with RANK and OPG: implications for bone remodeling and osteolytic bone metastasis.

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Title: TSP-1 interaction with RANK and OPG: implications for bone remodeling and osteolytic bone metastasis.
Authors: Carminati L; Laboratory of Tumor Microenvironment, Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Sangalli F; Laboratory of Medical Imaging, Department of Biomedical Engineering, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Urbinati C; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Longhi E; Laboratory of Tumor Microenvironment, Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Tomasoni G; Laboratory of Tumor Microenvironment, Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Borsotti P; Laboratory of Tumor Microenvironment, Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Midwood KS; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Carlessi E; Laboratory of Tumor Microenvironment, Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy., Rusnati M; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Consorzio Interuniversitario Biotecnologie (CIB), Unit of Brescia, Brescia, Italy., Taraboletti G; Laboratory of Tumor Microenvironment, Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy. giulia.taraboletti@marionegri.it.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 21; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-026-08600-9