ALS mutations disrupt self-association between the ubiquilin STI1 hydrophobic groove and internal placeholder sequences.
Saved in:
| Title: | ALS mutations disrupt self-association between the ubiquilin STI1 hydrophobic groove and internal placeholder sequences. |
|---|---|
| Authors: | Onwunma J; Department of Chemistry & Biochemistry, University of Toledo, Toledo, OH, USA., Binsabaan S; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA., Allen SP; Department of Chemistry & Biochemistry, University of Toledo, Toledo, OH, USA.; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA., Thanthirige SR; Department of Chemistry & Biochemistry, University of Toledo, Toledo, OH, USA.; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA., Gaur D; Department of Chemistry & Biochemistry, University of Toledo, Toledo, OH, USA.; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA., Sankaran B; Lawrence Berkeley National Lab, Berkeley Center for Structural Biology, Molecular Biophysics and Integrated Bioimaging, Berkeley, CA, USA., Wohlever ML; Department of Chemistry & Biochemistry, University of Toledo, Toledo, OH, USA. wohlever@pitt.edu.; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA. wohlever@pitt.edu. |
| Source: | The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2694-2711. Date of Electronic Publication: 2026 Mar 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1460-2075 |
|---|---|
| DOI: | 10.1038/s44318-026-00745-9 |
