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Phase separation of PGL-3 driven by structured domains that oligomerize and interact with RGG motifs.

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Title: Phase separation of PGL-3 driven by structured domains that oligomerize and interact with RGG motifs.
Authors: Kuroiwa R; Department of Molecular Biology and Genetics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA., Sharma P; Department of Chemistry, Johns Hopkins University, Baltimore, MD, 21218, USA.; Department of Biomedical Engineering, Washington University in Saint Louis, Saint Louis, MO, 63130, USA., Putnam AA; Department of Molecular Biology and Genetics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA., Fried SD; Department of Chemistry, Johns Hopkins University, Baltimore, MD, 21218, USA.; Thomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA., Seydoux G; Department of Molecular Biology and Genetics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA. gseydoux@jhmi.edu.
Source: EMBO reports [EMBO Rep] 2026 Apr; Vol. 27 (8), pp. 2061-2087. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kuroiwa+R%22">Kuroiwa R</searchLink>; Department of Molecular Biology and Genetics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Sharma+P%22">Sharma P</searchLink>; Department of Chemistry, Johns Hopkins University, Baltimore, MD, 21218, USA.; Department of Biomedical Engineering, Washington University in Saint Louis, Saint Louis, MO, 63130, USA.<br /><searchLink fieldCode="AU" term="%22Putnam+AA%22">Putnam AA</searchLink>; Department of Molecular Biology and Genetics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.<br /><searchLink fieldCode="AU" term="%22Fried+SD%22">Fried SD</searchLink>; Department of Chemistry, Johns Hopkins University, Baltimore, MD, 21218, USA.; Thomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.<br /><searchLink fieldCode="AU" term="%22Seydoux+G%22">Seydoux G</searchLink>; Department of Molecular Biology and Genetics, Johns Hopkins University, Howard Hughes Medical Institute, Baltimore, MD, 21205, USA. gseydoux@jhmi.edu.
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        Value: 10.1038/s44319-026-00730-7
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              Text: 2026 Apr
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