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Oral sodium butyrate supplementation acts on intestinal dysbiosis and resolves spinal cord neuroinflammation and nociceptive neuron sensitization.

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Title: Oral sodium butyrate supplementation acts on intestinal dysbiosis and resolves spinal cord neuroinflammation and nociceptive neuron sensitization.
Authors: Fusco A; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Ricciardi F; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Perrone M; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Di Martino E; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Limongelli R; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Morace AM; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Finamore R; Department of Experimental Medicine, Section of Biotechnology, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Bonsale R; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Belardo C; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Trotta MC; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Iannotti FA; Institute of Biomolecular Chemistry (ICB), National Research Council of Italy (CNR), 80078, Pozzuoli, NA, Italy., Infantino R; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.; Pharmacology and Therapeutics, School of Pharmacy and Medical Sciences, University of Galway, Galway, Ireland., Luongo L; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Schiraldi C; Department of Experimental Medicine, Section of Biotechnology, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Di Marzo V; Institute of Biomolecular Chemistry (ICB), National Research Council of Italy (CNR), 80078, Pozzuoli, NA, Italy.; Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health, Faculty of Medicine and Faculty of Agricultural and Food Sciences, Université Laval, Québec City, QC, Canada.; Heart and Lung Research Institute of Université Laval, Québec City, QC, Canada.; Institute for Nutrition and Functional Foods, Centre NUTRISS, Université Laval, Québec City, QC, Canada., Maione S; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Gatta A; Department of Experimental Medicine, Section of Biotechnology, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy., Guida F; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy. francesca.guida@unicampania.it.
Source: Journal of inflammation (London, England) [J Inflamm (Lond)] 2026 Mar 20; Vol. 23 (1). Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101232234 Publication Model: Electronic Cited Medium: Print ISSN: 1476-9255 (Print) Linking ISSN: 14769255 NLM ISO Abbreviation: J Inflamm (Lond) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Oral sodium butyrate supplementation acts on intestinal dysbiosis and resolves spinal cord neuroinflammation and nociceptive neuron sensitization.
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  Data: <searchLink fieldCode="AU" term="%22Fusco+A%22">Fusco A</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Ricciardi+F%22">Ricciardi F</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Perrone+M%22">Perrone M</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Martino+E%22">Di Martino E</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Limongelli+R%22">Limongelli R</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Morace+AM%22">Morace AM</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Finamore+R%22">Finamore R</searchLink>; Department of Experimental Medicine, Section of Biotechnology, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Bonsale+R%22">Bonsale R</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Belardo+C%22">Belardo C</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Trotta+MC%22">Trotta MC</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Iannotti+FA%22">Iannotti FA</searchLink>; Institute of Biomolecular Chemistry (ICB), National Research Council of Italy (CNR), 80078, Pozzuoli, NA, Italy.<br /><searchLink fieldCode="AU" term="%22Infantino+R%22">Infantino R</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.; Pharmacology and Therapeutics, School of Pharmacy and Medical Sciences, University of Galway, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Luongo+L%22">Luongo L</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Schiraldi+C%22">Schiraldi C</searchLink>; Department of Experimental Medicine, Section of Biotechnology, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Marzo+V%22">Di Marzo V</searchLink>; Institute of Biomolecular Chemistry (ICB), National Research Council of Italy (CNR), 80078, Pozzuoli, NA, Italy.; Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health, Faculty of Medicine and Faculty of Agricultural and Food Sciences, Université Laval, Québec City, QC, Canada.; Heart and Lung Research Institute of Université Laval, Québec City, QC, Canada.; Institute for Nutrition and Functional Foods, Centre NUTRISS, Université Laval, Québec City, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Maione+S%22">Maione S</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Gatta+A%22">Gatta A</searchLink>; Department of Experimental Medicine, Section of Biotechnology, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Guida+F%22">Guida F</searchLink>; Department of Experimental Medicine, Pharmacology Division, University of Campania 'L. Vanvitelli', 80138, Napoli, Italy. francesca.guida@unicampania.it.
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  Data: <searchLink fieldCode="JN" term="%22101232234%22">Journal of inflammation (London, England)</searchLink> [J Inflamm (Lond)] 2026 Mar 20; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 Mar 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101232234 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1476-9255 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214769255%22">14769255 </searchLink><i>NLM ISO Abbreviation: </i>J Inflamm (Lond) <i>Subsets: </i>PubMed not MEDLINE
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