Discovery and computational characterization of a novel cryptic pocket in human farnesyl pyrophosphate synthase.
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| Title: | Discovery and computational characterization of a novel cryptic pocket in human farnesyl pyrophosphate synthase. |
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| Authors: | Pandya V; Department of Biochemistry, Memorial University of Newfoundland, 45 Arctic Avenue, St. John's, Newfoundland and Labrador A1C 5S7, Canada., Wilson KA; Department of Biochemistry, Memorial University of Newfoundland, 45 Arctic Avenue, St. John's, Newfoundland and Labrador A1C 5S7, Canada., Leung CY; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada., Tsantrizos YS; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada., Park J; Department of Biochemistry, Memorial University of Newfoundland, 45 Arctic Avenue, St. John's, Newfoundland and Labrador A1C 5S7, Canada. Electronic address: Jaeok.park@mun.ca. |
| Source: | Journal of structural biology [J Struct Biol] 2026 Jun; Vol. 218 (2), pp. 108316. Date of Electronic Publication: 2026 Mar 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Academic Press Country of Publication: United States NLM ID: 9011206 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8657 (Electronic) Linking ISSN: 10478477 NLM ISO Abbreviation: J Struct Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1095-8657 |
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| DOI: | 10.1016/j.jsb.2026.108316 |
