GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model.

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Title: GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model.
Authors: Hutschalik T; Ncardia Services B.V., Leiden, Netherlands.; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands., Dasí A; Department of Computer Science, University of Oxford, Oxford, United Kingdom., Riebel LL; Department of Computer Science, University of Oxford, Oxford, United Kingdom., Wiendels M; Anatomy and Embryology, Leiden University Medical Center (LUMC), Leiden, Netherlands., Bakker F; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Beckers LJAM; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Kriege KC; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Valster SM; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Vulders RCM; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Özgül O; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands., Peyronnet R; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg Bad Krozingen, and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Rodriguez B; Department of Computer Science, University of Oxford, Oxford, United Kingdom., Argenziano M; Ncardia Services B.V., Leiden, Netherlands., Schotten U; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.; Department of Cardiology, Maastricht University Medical Center, Maastricht, Netherlands., Matsa E; Ncardia Services B.V., Leiden, Netherlands.; Cellistic, Mont-Saint-Guibert, Belgium.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.; National Institute for Bioprocessing Research and Training, Dublin, Ireland.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 06; Vol. 16, pp. 1719392. Date of Electronic Publication: 2026 Mar 06 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1719392