GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model.

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Title: GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model.
Authors: Hutschalik T; Ncardia Services B.V., Leiden, Netherlands.; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands., Dasí A; Department of Computer Science, University of Oxford, Oxford, United Kingdom., Riebel LL; Department of Computer Science, University of Oxford, Oxford, United Kingdom., Wiendels M; Anatomy and Embryology, Leiden University Medical Center (LUMC), Leiden, Netherlands., Bakker F; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Beckers LJAM; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Kriege KC; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Valster SM; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Vulders RCM; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands., Özgül O; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands., Peyronnet R; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg Bad Krozingen, and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Rodriguez B; Department of Computer Science, University of Oxford, Oxford, United Kingdom., Argenziano M; Ncardia Services B.V., Leiden, Netherlands., Schotten U; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.; Department of Cardiology, Maastricht University Medical Center, Maastricht, Netherlands., Matsa E; Ncardia Services B.V., Leiden, Netherlands.; Cellistic, Mont-Saint-Guibert, Belgium.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.; National Institute for Bioprocessing Research and Training, Dublin, Ireland.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 06; Vol. 16, pp. 1719392. Date of Electronic Publication: 2026 Mar 06 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: GJA5 and ATP1A1 perturbations recapitulate inflammation-related beat irregularities in iPSC-based atrial myocardium tissue model.
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  Data: <searchLink fieldCode="AU" term="%22Hutschalik+T%22">Hutschalik T</searchLink>; Ncardia Services B.V., Leiden, Netherlands.; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Dasí+A%22">Dasí A</searchLink>; Department of Computer Science, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Riebel+LL%22">Riebel LL</searchLink>; Department of Computer Science, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wiendels+M%22">Wiendels M</searchLink>; Anatomy and Embryology, Leiden University Medical Center (LUMC), Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bakker+F%22">Bakker F</searchLink>; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Beckers+LJAM%22">Beckers LJAM</searchLink>; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Kriege+KC%22">Kriege KC</searchLink>; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Valster+SM%22">Valster SM</searchLink>; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vulders+RCM%22">Vulders RCM</searchLink>; Department of Digital Standardization and Licensing Research, Intellectual Property and Standards, Royal Philips, Eindhoven, Netherlands.<br /><searchLink fieldCode="AU" term="%22Özgül+O%22">Özgül O</searchLink>; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Peyronnet+R%22">Peyronnet R</searchLink>; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg Bad Krozingen, and Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rodriguez+B%22">Rodriguez B</searchLink>; Department of Computer Science, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Argenziano+M%22">Argenziano M</searchLink>; Ncardia Services B.V., Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Schotten+U%22">Schotten U</searchLink>; Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, Netherlands.; Department of Cardiology, Maastricht University Medical Center, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Matsa+E%22">Matsa E</searchLink>; Ncardia Services B.V., Leiden, Netherlands.; Cellistic, Mont-Saint-Guibert, Belgium.; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.; National Institute for Bioprocessing Research and Training, Dublin, Ireland.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Mar 06; Vol. 16, pp. 1719392. <i>Date of Electronic Publication: </i>2026 Mar 06 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2025.1719392
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              Text: 2026 Mar 06
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