Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1-mediated P53 ubiquitination.
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| Title: | Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1-mediated P53 ubiquitination. |
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| Authors: | Li Y; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Liang W; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Xu Y; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Han Y; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Zhao W; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Wang S; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Deng W; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Qin C; NHC Key Laboratory of Comparative Medicine, National Human Diseases Animal Model Resource Center, National Center of Technology Innovation for Animal Model; Key Laboratory of Pathogen Infection Prevention and Control (Peking Union Medical College), Ministry of Education, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; Changping National Laboratory (CPNL), Beijing, China.; State Key Laboratory of Respiratory Health and Multimorbidity, Beijing, China. |
| Source: | Animal models and experimental medicine [Animal Model Exp Med] 2026 Mar; Vol. 9 (3), pp. 558-571. Date of Electronic Publication: 2026 Mar 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101726292 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2576-2095 (Electronic) Linking ISSN: 25762095 NLM ISO Abbreviation: Animal Model Exp Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2576-2095 |
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| DOI: | 10.1002/ame2.70165 |
