RNAi-mediated p38δ silencing mitigates anthracycline cardiotoxicity in female mice.
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| Title: | RNAi-mediated p38δ silencing mitigates anthracycline cardiotoxicity in female mice. |
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| Authors: | Trampel KA; Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, United States., Gross KY; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States., O'Reilly D; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States.; Sealey Institute for Drug Discovery, University of Texas Medical Branch, Galveston, Texas, United States., Melisova A; Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, United States., Salman B; Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, United States., Green S; Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, United States., George SA; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Khvorova A; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States.; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States., Efimov IR; Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, United States., Efimova T; Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, United States. |
| Source: | American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2026 May 01; Vol. 330 (5), pp. H1522-H1539. Date of Electronic Publication: 2026 Mar 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901228 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1539 (Electronic) Linking ISSN: 03636135 NLM ISO Abbreviation: Am J Physiol Heart Circ Physiol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1522-1539 |
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| DOI: | 10.1152/ajpheart.00944.2025 |
