Antithrombotic Therapy Discontinuation, Bleeding, and Thromboembolic Events in Patients With Cancer During the Last Phase of Life: Insights From Primary Care Records.

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Title: Antithrombotic Therapy Discontinuation, Bleeding, and Thromboembolic Events in Patients With Cancer During the Last Phase of Life: Insights From Primary Care Records.
Authors: Abbel D; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands n.t.abbel@lumc.nl.; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands., Geersing GJ; University Medical Center Utrecht, Department of General Practice and Nursing Science, Utrecht University, Utrecht, The Netherlands., Trinks-Roerdink EM; University Medical Center Utrecht, Department of General Practice and Nursing Science, Utrecht University, Utrecht, The Netherlands., Aldridge SJ; Population Data Science, Swansea University Medical School, Faculty of Medicine, Health, and Life Science, Swansea University, Swansea, United Kingdom., Edwards A; PRIME Centre Wales, Division of Population Medicine, Cardiff University, Cardiff, United Kingdom., Geijteman ECT; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Goedegebuur J; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Gussekloo J; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands., Kempers EK; Department of Hematology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands., Klok FA; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands., Kruip MJHA; Department of Hematology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands., Mahé I; Paris Cité University, Assistance-Publique-Hôpitaux de Paris (AP-HP), Service de Médecine Interne, Hôpital Louis-Mourier; Inserm The Paris Cardiovascular Research Center, Paris, France., Mooijaart SP; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands., Noble S; Marie Curie Palliative Care Research Centre, Division of Population, School of Medicine, Cardiff University, Cardiff, United Kingdom., Ording AG; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark., Portielje JEA; Department of Medicine, Section of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands., Szmit S; Department of Cardio-Oncology, Centre of Postgraduate Medical Education, Warsaw, Poland., Søgaard M; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark.; Center for General Practice, Aalborg University, Aalborg, Denmark., Trompet S; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands., Cannegieter SC; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., van den Dries CJ; University Medical Center Utrecht, Department of General Practice and Nursing Science, Utrecht University, Utrecht, The Netherlands.
Source: Annals of family medicine [Ann Fam Med] 2026 Mar 23; Vol. 24 (2), pp. 104-110. Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article
Journal Info: Publisher: Annals of Family Medicine, Inc Country of Publication: United States NLM ID: 101167762 Publication Model: Electronic Cited Medium: Internet ISSN: 1544-1717 (Electronic) Linking ISSN: 15441709 NLM ISO Abbreviation: Ann Fam Med Subsets: MEDLINE
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  Data: Antithrombotic Therapy Discontinuation, Bleeding, and Thromboembolic Events in Patients With Cancer During the Last Phase of Life: Insights From Primary Care Records.
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  Data: <searchLink fieldCode="AU" term="%22Abbel+D%22">Abbel D</searchLink>; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands n.t.abbel@lumc.nl.; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Geersing+GJ%22">Geersing GJ</searchLink>; University Medical Center Utrecht, Department of General Practice and Nursing Science, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Trinks-Roerdink+EM%22">Trinks-Roerdink EM</searchLink>; University Medical Center Utrecht, Department of General Practice and Nursing Science, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Aldridge+SJ%22">Aldridge SJ</searchLink>; Population Data Science, Swansea University Medical School, Faculty of Medicine, Health, and Life Science, Swansea University, Swansea, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Edwards+A%22">Edwards A</searchLink>; PRIME Centre Wales, Division of Population Medicine, Cardiff University, Cardiff, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Geijteman+ECT%22">Geijteman ECT</searchLink>; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Goedegebuur+J%22">Goedegebuur J</searchLink>; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gussekloo+J%22">Gussekloo J</searchLink>; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kempers+EK%22">Kempers EK</searchLink>; Department of Hematology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Klok+FA%22">Klok FA</searchLink>; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kruip+MJHA%22">Kruip MJHA</searchLink>; Department of Hematology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mahé+I%22">Mahé I</searchLink>; Paris Cité University, Assistance-Publique-Hôpitaux de Paris (AP-HP), Service de Médecine Interne, Hôpital Louis-Mourier; Inserm The Paris Cardiovascular Research Center, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mooijaart+SP%22">Mooijaart SP</searchLink>; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Noble+S%22">Noble S</searchLink>; Marie Curie Palliative Care Research Centre, Division of Population, School of Medicine, Cardiff University, Cardiff, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ording+AG%22">Ording AG</searchLink>; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Portielje+JEA%22">Portielje JEA</searchLink>; Department of Medicine, Section of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Szmit+S%22">Szmit S</searchLink>; Department of Cardio-Oncology, Centre of Postgraduate Medical Education, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Søgaard+M%22">Søgaard M</searchLink>; Danish Center for Health Services Research, Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark.; Center for General Practice, Aalborg University, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Trompet+S%22">Trompet S</searchLink>; Department of Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands.; LUMC Center for Medicine for Older People, Leiden University Medical Center, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cannegieter+SC%22">Cannegieter SC</searchLink>; Department of Medicine, Section of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Dries+CJ%22">van den Dries CJ</searchLink>; University Medical Center Utrecht, Department of General Practice and Nursing Science, Utrecht University, Utrecht, The Netherlands.
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