Exploratory characterization of gut microbiota and cognitive profiles in adolescents with subthreshold depression: a shotgun metagenomics sequencing study.
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| Title: | Exploratory characterization of gut microbiota and cognitive profiles in adolescents with subthreshold depression: a shotgun metagenomics sequencing study. |
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| Authors: | Wang R; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Ma R; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Cai Y; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, PR China., Zhang L; Center of Mental Health, The Third People's Hospital of Liupanshui, Liupanshui, PR China., Lu W; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Zheng W; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Kong J; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Miao Q; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Li X; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Guan L; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Gao Y; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Chen K; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Kwan ATH; Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Brain and Cognition Discovery Foundation, Toronto, ON, Canada., McIntyre RS; Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Brain and Cognition Discovery Foundation, Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Xu G; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China., Yu CK; Department of Counselling and Psychology, Hong Kong Shue Yan University, Hong Kong, PR China., Lam BY; Department of Counselling and Psychology, Hong Kong Shue Yan University, Hong Kong, PR China., So KF; Ministry of Education Joint International Research Laboratory of CNS Regeneration, Jinan University, Guangzhou, PR China., Lin K; Department of Affective Disorder, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, PR China. klin@cuhk.edu.cn.; Guangdong Engineering Technology Research Center for Translational Medicine of MentalDisorders, Guangzhou, PR China. klin@cuhk.edu.cn.; Department of Psychiatry and Behavioral Sciences, School of Medicine, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong, PR China. klin@cuhk.edu.cn.; Lecong Hospital of Shunde, Foshan, PR China. klin@cuhk.edu.cn. |
| Source: | Npj mental health research [Npj Ment Health Res] 2026 Mar 24; Vol. 5 (1). Date of Electronic Publication: 2026 Mar 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 9918592488906676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-4251 (Electronic) Linking ISSN: 27314251 NLM ISO Abbreviation: Npj Ment Health Res Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2731-4251 |
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| DOI: | 10.1038/s44184-026-00202-9 |