Stress-induced OMA1-mediated cleavage of AIFM1 suppresses cell growth by controlling mitochondrial OXPHOS activity.
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| Title: | Stress-induced OMA1-mediated cleavage of AIFM1 suppresses cell growth by controlling mitochondrial OXPHOS activity. |
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| Authors: | Nishigori M; Department of Chemistry, Faculty of Science, Fukuoka University, Fukuoka, Japan.; Division of Biology, Faculty of Science, Fukuoka University, Fukuoka, Japan., Hirata S; Department of Chemistry, Faculty of Science, Fukuoka University, Fukuoka, Japan., Kosako H; Division of Cell Signaling, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.; Laboratory of Proteomics, Institute of Photonics and Human Health Frontier, Tokushima University, Tokushima, Japan., Ichinohe T; Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Nolte H; Max Planck Institute for Biology of Ageing, Cologne, Germany., Riemer J; Redox Metabolism, Institute of Biochemistry and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Langer T; Max Planck Institute for Biology of Ageing, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Koshiba T; Department of Chemistry, Faculty of Science, Fukuoka University, Fukuoka, Japan. koshiba@kyudai.jp.; Division of Biology, Faculty of Science, Fukuoka University, Fukuoka, Japan. koshiba@kyudai.jp. |
| Source: | The EMBO journal [EMBO J] 2026 Jun; Vol. 45 (11), pp. 3655-3698. Date of Electronic Publication: 2026 Mar 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-026-00734-y |
