View in EDS

Molecular characterization of humanized APOE mouse models reveals source and genotype dependent differences.

Saved in:
Bibliographic Details
Title: Molecular characterization of humanized APOE mouse models reveals source and genotype dependent differences.
Authors: Wang N; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Yu G; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wang Z; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Alnobani A; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Jeevaratnam S; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Zhang X; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., McReynolds M; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Chang Y; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Qi F; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Tauer W; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Rosenberg C; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Wren M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Ikezu TC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Martens YA; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Wang M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zhang B; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Carter GW; The Jackson Laboratory, Bar Harbor, ME, USA., Sasner M; The Jackson Laboratory, Bar Harbor, ME, USA., Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA., Peng J; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA., Wu LJ; Department of Neurology, Mayo Clinic, Rochester, MN, USA.; Center for Neuroimmunology and Glial Biology, Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX, USA., Kanekiyo T; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. kanekiyo.takahisa@mayo.edu., Liu CC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. jenfttt13@gmail.com., Bu G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. gbu@ust.hk.; Division of Life Science and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. gbu@ust.hk.
Source: Molecular neurodegeneration [Mol Neurodegener] 2026 Mar 24; Vol. 21 (1). Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41877131
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Molecular characterization of humanized APOE mouse models reveals source and genotype dependent differences.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Yu+G%22">Yu G</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Alnobani+A%22">Alnobani A</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Jeevaratnam+S%22">Jeevaratnam S</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22McReynolds+M%22">McReynolds M</searchLink>; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chang+Y%22">Chang Y</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Qi+F%22">Qi F</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Tauer+W%22">Tauer W</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+C%22">Rosenberg C</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wren+M%22">Wren M</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ikezu+TC%22">Ikezu TC</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Martens+YA%22">Martens YA</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Carter+GW%22">Carter GW</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Sasner+M%22">Sasner M</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Peng+J%22">Peng J</searchLink>; Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wu+LJ%22">Wu LJ</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.; Center for Neuroimmunology and Glial Biology, Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kanekiyo+T%22">Kanekiyo T</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. kanekiyo.takahisa@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Liu+CC%22">Liu CC</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. jenfttt13@gmail.com.<br /><searchLink fieldCode="AU" term="%22Bu+G%22">Bu G</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. gbu@ust.hk.; Division of Life Science and State Key Laboratory of Nervous System Disorders, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. gbu@ust.hk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101266600%22">Molecular neurodegeneration</searchLink> [Mol Neurodegener] 2026 Mar 24; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Mar 24.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101266600 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1750-1326 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217501326%22">17501326 </searchLink><i>NLM ISO Abbreviation: </i>Mol Neurodegener <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41877131
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s13024-026-00940-6
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Molecular characterization of humanized APOE mouse models reveals source and genotype dependent differences.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wang N
      – PersonEntity:
          Name:
            NameFull: Yu G
      – PersonEntity:
          Name:
            NameFull: Wang Z
      – PersonEntity:
          Name:
            NameFull: Alnobani A
      – PersonEntity:
          Name:
            NameFull: Jeevaratnam S
      – PersonEntity:
          Name:
            NameFull: Zhang X
      – PersonEntity:
          Name:
            NameFull: McReynolds M
      – PersonEntity:
          Name:
            NameFull: Chang Y
      – PersonEntity:
          Name:
            NameFull: Qi F
      – PersonEntity:
          Name:
            NameFull: Tauer W
      – PersonEntity:
          Name:
            NameFull: Rosenberg C
      – PersonEntity:
          Name:
            NameFull: Wren M
      – PersonEntity:
          Name:
            NameFull: Ikezu TC
      – PersonEntity:
          Name:
            NameFull: Martens YA
      – PersonEntity:
          Name:
            NameFull: Wang M
      – PersonEntity:
          Name:
            NameFull: Zhang B
      – PersonEntity:
          Name:
            NameFull: Carter GW
      – PersonEntity:
          Name:
            NameFull: Sasner M
      – PersonEntity:
          Name:
            NameFull: Holtzman DM
      – PersonEntity:
          Name:
            NameFull: Peng J
      – PersonEntity:
          Name:
            NameFull: Wu LJ
      – PersonEntity:
          Name:
            NameFull: Kanekiyo T
      – PersonEntity:
          Name:
            NameFull: Liu CC
      – PersonEntity:
          Name:
            NameFull: Bu G
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 24
              M: 03
              Text: 2026 Mar 24
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1750-1326
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Molecular neurodegeneration
              Type: main
ResultId 1