CAFs-derived LAM332 promotes CTCs formation and survival via ITGA3 and contributes to the metastasis of pancreatic ductal adenocarcinoma.

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Title: CAFs-derived LAM332 promotes CTCs formation and survival via ITGA3 and contributes to the metastasis of pancreatic ductal adenocarcinoma.
Authors: Tang H; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China., Shi W; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China., Tan S; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China., Zhang Z; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China., Zhang Q; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China., Zhou P; Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China., Wang Y; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China., Lei Z; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China., Hu F; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China., Gao S; Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Southeast University, Nanjing, China., Zhou J; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China. zhoujh@seu.edu.cn.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China. zhoujh@seu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 25; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CAFs-derived LAM332 promotes CTCs formation and survival via ITGA3 and contributes to the metastasis of pancreatic ductal adenocarcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Tang+H%22">Tang H</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Shi+W%22">Shi W</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Tan+S%22">Tan S</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhou+P%22">Zhou P</searchLink>; Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Lei+Z%22">Lei Z</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Hu+F%22">Hu F</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Zhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Department of Surgery, School of Medicine, Southeast University, Nanjing, Jiangsu, China. zhoujh@seu.edu.cn.; Department of Hepato-Pancreatico-Biliary Surgery, Zhongda Hospital Southeast University, Nanjing, Jiangsu, China. zhoujh@seu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Mar 25; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41881953
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        Value: 10.1038/s41419-026-08642-z
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        Text: English
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      – TitleFull: CAFs-derived LAM332 promotes CTCs formation and survival via ITGA3 and contributes to the metastasis of pancreatic ductal adenocarcinoma.
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            – D: 25
              M: 03
              Text: 2026 Mar 25
              Type: published
              Y: 2026
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