SMARCA4 promotes lineage plasticity and enzalutamide resistance in prostate cancer by regulating PROX1 via H3K27 acetylation.
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| Title: | SMARCA4 promotes lineage plasticity and enzalutamide resistance in prostate cancer by regulating PROX1 via H3K27 acetylation. |
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| Authors: | Wu C; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Luo M; Department of Urology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China., Wu C; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Yuan Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Li Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Liao Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Zhang Y; Department of Urology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China., Huang X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.; Department of Urology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, Jiangxi, China., Wang M; Department of Urology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China., Lv S; Department of Urology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China. lsd990@smu.edu.cn.; Department of Urology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, Jiangxi, China. lsd990@smu.edu.cn., Wei Q; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. qwei@smu.edu.cn.; Department of Urology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China. qwei@smu.edu.cn.; Department of Urology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, Jiangxi, China. qwei@smu.edu.cn. |
| Source: | Cell death discovery [Cell Death Discov] 2026 Mar 25; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-026-03068-0 |
