A novel PAAoptosis-inducing ERRα-targeting compound for combating hematopoietic and solid cancers.

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Title: A novel PAAoptosis-inducing ERRα-targeting compound for combating hematopoietic and solid cancers.
Authors: Seo W; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea.; Division of Hematology/Oncology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Heo Y; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea., Tran KV; Department of Nuclear Medicine, Chonnam National University Medical school, Hwasun, Republic of Korea.; Department of Biomedical Science (BrainKorea21 Plus), Chonnam National University Graduate School, Gwangju, Republic of Korea., Kim SY; Department of Nuclear Medicine, Chonnam National University Medical school, Hwasun, Republic of Korea., Bae EJ; SK Chemicals Co., Ltd., Seoul, Republic of Korea., Jung B; Department of Pre-medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Lee SH; Center for Bio-imaging & Translational Research (104-Dong), Korea Basic Science Institute, Cheongju, South Korea.; Department of Chemistry, Hanyang University, Seoul, Republic of Korea., Roh T; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Jeon SM; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Kim KT; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Park EJ; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Kim SI; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Koh JS; Division of Hematology/Oncology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Song IC; Division of Hematology/Oncology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Song HK; Department of Life Sciences, Korea University, Seoul, Republic of Korea., Min JJ; Department of Nuclear Medicine, Chonnam National University Medical school, Hwasun, Republic of Korea. jjminmd@gmail.com., Ahn JH; Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea. jhahn@gist.ac.kr., Jo EK; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea. hayoungj@cnu.ac.kr.
Source: Cell death discovery [Cell Death Discov] 2026 Mar 26; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2058-7716
DOI:10.1038/s41420-026-03010-4