Solubility based mechanistic profiling of combinatorial drug therapy.
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| Title: | Solubility based mechanistic profiling of combinatorial drug therapy. |
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| Authors: | Gholizadeh E; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Zangene E; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Vadadokhau U; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Ritz D; Biozentrum, University of Basel, Basel, Switzerland., Miettinen JJ; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Soliymani R; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Baumann M; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Wilhelm M; Technical University of Munich, Munich, Germany.; Munich Data Science Institute (MDSI), Garching, Germany., Kankuri E; Department of Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Haynes PA; School of Natural Sciences, Macquarie University, North Ryde, New South Wales, 2109, Australia., Heckman CA; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; iCAN Digital Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland., Saei AA; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Jafari M; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland. mohieddin.jafari@helsinki.fi.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. mohieddin.jafari@helsinki.fi.; TAYS Cancer Center, Tampere, Finland. mohieddin.jafari@helsinki.fi.; Tampere Institute for Advanced Study, Tampere University, Tampere, Finland. mohieddin.jafari@helsinki.fi. |
| Source: | Nature communications [Nat Commun] 2026 Mar 25; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-026-70394-3 |
