CU104, a novel barrier function enhancer, improves colitis via modulation of barrier function and immune cell recruitment.

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Title: CU104, a novel barrier function enhancer, improves colitis via modulation of barrier function and immune cell recruitment.
Authors: Park IS; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim JH; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim D; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea., Kim YW; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Shin Y; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim KB; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Zhang H; Curacle Co. Ltd, Seoul, Republic of Korea., Kim TI; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim SW; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea., Kwon YG; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.; Curacle Co. Ltd, Seoul, Republic of Korea., Cheon JH; Department of Internal Medicine and Institute of Gastroenterology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 10; Vol. 17, pp. 1767762. Date of Electronic Publication: 2026 Mar 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1767762