PRMT5 inhibition triggers functional ATM deficiency and sensitizes pancreatic cancer to CHK1 blockade.
Saved in:
| Title: | PRMT5 inhibition triggers functional ATM deficiency and sensitizes pancreatic cancer to CHK1 blockade. |
|---|---|
| Authors: | Dzikowski M; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, United States., Pollin G; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Surgery, Division of Research, Medical College of Wisconsin, Milwaukee, WI, United States., Gunia V; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Surgery, Division of Research, Medical College of Wisconsin, Milwaukee, WI, United States., Butler S; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States., Enkhtuul B; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, United States., Gavina Chavez J; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States., Zimmermann MT; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.; Data Science Institute, Medical College of Wisconsin, Milwaukee, WI, United States., Mathison A; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Surgery, Division of Research, Medical College of Wisconsin, Milwaukee, WI, United States., Urrutia R; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Surgery, Division of Research, Medical College of Wisconsin, Milwaukee, WI, United States.; Departments of Biochemistry, Biophysics, and Physiology, Medical College of Wisconsin, Milwaukee, WI, United States., Lomberk G; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI, United States.; Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI, United States.; Department of Surgery, Division of Research, Medical College of Wisconsin, Milwaukee, WI, United States. |
| Source: | Frontiers in cell and developmental biology [Front Cell Dev Biol] 2026 Mar 11; Vol. 14, pp. 1748541. Date of Electronic Publication: 2026 Mar 11 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2296-634X |
|---|---|
| DOI: | 10.3389/fcell.2026.1748541 |
